Is vitamin D toxic to cats?
Also called: vitamin D3, cholecalciferol, psoriasis cream, calcipotriol, calcipotriene, calcitriol, vitamin D supplement
Toxic
Can raise calcium to life-threatening levels and injure the kidneys.
Yes. Vitamin D3 supplements and some psoriasis creams (calcipotriol, calcipotriene, calcitriol) can raise a cat's calcium to dangerous levels, which often injures the kidneys.
Signs to watch for
- Stomach upset, more drinking and peeing, and dangerously high calcium.
Where this comes from
VCA Animal Hospitals
Vitamin D3 poisoning can cause stomach upset, increased thirst and urination, and a life-threatening elevation of calcium (hypercalcemia).
In cats, severe hypercalcemia often leads to kidney injury.
Read "Household Hazards – Toxic Hazards for Cats"
Checked 9 October 2026
Where this comes from
VCA Animal Hospitals
Exposures to Vitamin D3 (cholecalciferol) occur after ingestion of vitamin D3 supplements, rat/mouse bait containing cholecalciferol
some topical creams used for psoriasis (containing calcitriol, calcipotriene, or calcipotriol)
In cats, severe hypercalcemia often leads to kidney injury.
Read "Household Hazards – Toxic Hazards for Cats"
Checked 9 October 2026
International Cat Care
Human medicines such as laxatives, aspirin, paracetamol, ibuprofen, minoxidil, psoriasis creams, 5-fluorouracil and antidepressants.
Checked 9 October 2026
Where this comes from
International Cat Care
If you’re concerned your cat has come into contact with any of the substances listed, contact your veterinary team immediately
Checked 9 October 2026
Where this comes from
VCA Animal Hospitals
Vitamin D3 poisoning can cause stomach upset, increased thirst and urination, and a life-threatening elevation of calcium (hypercalcemia).
Read "Household Hazards – Toxic Hazards for Cats"
Checked 9 October 2026