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Are antidepressants toxic to cats?

Also called: antidepressant, Prozac, fluoxetine, Zoloft, sertraline, Effexor, venlafaxine, Cymbalta

Toxic

Can poison cats, and cats seem to like the taste of some of them.

Yes. Antidepressants such as Prozac, Zoloft, Effexor and Cymbalta can be highly poisonous to cats, and cats seem to like the taste of some antidepressants and ADHD medicines.

Signs to watch for

  • Loss of appetite, lethargy, vomiting, tremors, seizures, high body temperature and diarrhoea.
  • Overstimulation of the heart and nervous system.

Sources

  • List of Things Toxic to CatsPet Poison Helpline · Read 9 October 2026
    Antidepressants such as Prozac, Zoloft, Effexor, and Cymbalta can be highly poisonous to cats.
    If ingested, cats may experience anorexia, lethargy, vomiting, tremors, seizures, hyperthermia, and diarrhea.
  • Household Hazards – Toxic Hazards for CatsVCA Animal Hospitals · Read 9 October 2026
    Ingestion of these medications may lead to cardiovascular and neurologic stimulation.
    Cats seem to like the taste of certain antidepressants (e.g., Effexor) and ADHD medications (e.g., Adderall)
  • Cats and poisonsInternational Cat Care · Read 9 October 2026
    If you’re concerned your cat has come into contact with any of the substances listed, contact your veterinary team immediately
    Never give cats products intended for people , unless instructed otherwise by your vet.

Information from Pet Poison Helpline, VCA Animal Hospitals and International Cat CareSources checked 9 October 2026

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